CHEMBL1928134


SMILES CCOCCOc1ccn2ncc(C(=O)NCCCCN3CCN(c4ccccc4OC)CC3)c2c1
InChIKey PKJVDKUHFZYEMN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 13
Molecular weight (Da) 495.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.75 8.13 8.52 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.18 9.18 9.18 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.8 5.8 5.8 ChEMBL
α1A Q9TSW7 Pig Adrenoceptors A pKi 8.92 8.92 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database