CHF-6366


SMILES O=C(O[C@@H]1C2CCN(CC2)C1)N[C@@H](c1ccccc1)c1cc(OCc2cc(C(=O)OCCCCNC[C@H](O)c3c4ccc(=O)[nH]c4c(O)cc3)nn2C)ccc1
InChIKey YWSIONULMMKTSJ-UZGNFBRWSA-N

Chemical properties

Hydrogen bond acceptors 12
Hydrogen bond donors 5
Rotatable bonds 16
Molecular weight (Da) 764.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKd 10.2 10.2 10.2 Guide to Pharmacology
β2 ADRB2 Human Adrenoceptors A pKd 11.4 11.4 11.4 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.2 10.2 10.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β2 ADRB2 Guinea pig Adrenoceptors A pIC50 10.1 10.1 10.1 ChEMBL