CHEMBL207543
SMILES | Clc1ccc(N2CCN(Cc3cn4nc(N5CCCCC5)ccc4n3)CC2)cc1Cl |
InChIKey | ACHQQXOLWIKHRK-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 444.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.92 | 6.92 | 6.92 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.07 | 6.07 | 6.07 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.96 | 6.05 | 6.15 | ChEMBL |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.66 | 5.66 | 5.66 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |