CHEMBL1946125


SMILES Fc1ccc(SCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1
InChIKey PXQSRAWVKJTJBP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 378.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.49 7.49 7.49 ChEMBL
H1 HRH1 Human Histamine A pKi 6.1 6.1 6.1 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.99 5.99 5.99 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.12 6.12 6.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database