CHEMBL1946253


SMILES Fc1ccc(CCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1
InChIKey FVMDOYQNOWAVCQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.91 6.91 6.91 ChEMBL
H1 HRH1 Human Histamine A pKi 5.9 5.9 5.9 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.39 5.39 5.39 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.04 7.04 7.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database