CHEMBL1946255


SMILES Clc1ccc(N2CCCN(CCCc3nc4ccccc4s3)CC2)cc1
InChIKey OUSOPIMSKOMYQI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 385.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.37 6.37 6.37 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.69 5.69 5.69 ChEMBL
H1 HRH1 Human Histamine A pKi 6.18 6.18 6.18 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.67 6.67 6.67 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database