CHEMBL1946745


SMILES OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCCc1nc2ccccc2s1
InChIKey SJEXSMOVRPPLBZ-VXMMSVGHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.37 6.37 6.37 ChEMBL
H1 HRH1 Human Histamine A pKi 6.73 6.73 6.73 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.89 7.89 7.89 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.36 7.36 7.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database