CHEMBL194849


SMILES Cc1ccc(N(NC2=NCCN2)c2cccc(O)c2)cc1
InChIKey ONSCHPQYHGOIQX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 282.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.07 6.07 6.07 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.3 7.3 7.3 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 7.75 7.75 7.75 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.89 7.89 7.89 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.57 7.57 7.57 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.62 7.62 7.62 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database