CHEMBL195110


SMILES O=C(N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1)N1CCCC1
InChIKey VFJOTTZGMDRNPT-MUUNZHRXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 613.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.16 5.16 5.16 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.8 6.8 6.8 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.17 6.17 6.17 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database