CHEMBL209034


SMILES Clc1ccc2nc(CN3CCN(c4ccc(Cl)c(Cl)c4)CC3)cn2n1
InChIKey YJBGSZUYOGPUMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 395.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.92 5.92 5.92 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.82 5.82 5.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.89 8.89 8.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.96 6.06 6.17 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.44 6.44 6.44 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.82 5.82 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database