CHEMBL1951664


SMILES CCc1ccc(-n2ccc3c(sc4nccc(N(C)C)c43)c2=O)cc1
InChIKey QQYIWENGMXJJRT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 349.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 8.09 8.09 8.09 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 6.29 6.29 6.29 ChEMBL