CHEMBL1956202


SMILES CC(=O)c1ccccc1OC(C)C1=NCCN1
InChIKey LHYRGWVECGKEOM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 232.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.21 5.21 5.21 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.13 5.13 5.13 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.99 5.99 5.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 6.53 6.53 6.53 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 6.7 6.7 6.7 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.2 7.2 7.2 ChEMBL