CHEMBL210232


SMILES COc1ccccc1N1CCN(Cc2cn(-c3ccccc3)nn2)CC1
InChIKey PDQWDSWLQAHIBM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.57 4.57 4.57 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.57 8.57 8.57 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 7.06 7.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database