CHEMBL211135
SMILES | Clc1ccc(N2CCN(Cc3cn4nc(Cl)ccc4n3)CC2)cc1 |
InChIKey | AGMWTWZTMQSDHF-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 3 |
Molecular weight (Da) | 361.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
5-HT2A | 5HT2A | Pig | 5-Hydroxytryptamine | A | pKi | 6.04 | 6.04 | 6.04 | ChEMBL |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.26 | 5.26 | 5.26 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 8.7 | 8.7 | 8.7 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 6.41 | 6.41 | 6.41 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 4.92 | 5.0 | 5.09 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.11 | 5.11 | 5.11 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |