CHEMBL197195


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc(F)n1
InChIKey HZYGVALVFFNNGE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 424.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.01 7.01 7.01 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.05 8.05 8.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.24 7.3 7.36 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.04 6.04 6.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database