CHEMBL197214


SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc(F)n2)CC1
InChIKey VQBXPTGVNAAIHI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.39 5.39 5.39 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.12 7.12 7.12 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.07 7.07 7.07 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.4 6.49 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database