CHEMBL197947


SMILES CCc1c(C(=O)N2CCc3cc4ccnc(N5CCN6CCC[C@@H]6C5)c4cc32)cnn1-c1ccc(C#N)cc1
InChIKey GXMYCNTVOUYSEA-RUZDIDTESA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 517.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database