CHEMBL200349


SMILES CCCn1c(=O)c2nc(-c3cnn(Cc4nc(-c5ccc(C)cc5)no4)c3)[nH]c2n(CCC)c1=O
InChIKey RLXWTYPPMJNURK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 474.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2B AA2BR Human Adenosine A pKi 7.27 7.27 7.27 ChEMBL
A3 AA3R Human Adenosine A pKi 5.06 5.06 5.06 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.52 5.52 5.52 ChEMBL
A1 AA1R Human Adenosine A pKi 5.58 5.58 5.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database