CHEMBL1091875


SMILES CN[C@H]1CCN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1
InChIKey POXFWGOYGQTRMD-VIFPVBQESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 317.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 8.7 8.7 8.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pIC50 7.89 8.14 8.4 ChEMBL