CHEMBL2031877


SMILES C[C@H]1CCCN1C(=O)c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1
InChIKey QKNQLRSRULGFBA-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 431.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.15 5.15 5.15 ChEMBL
H3 HRH3 Human Histamine A pKi 8.77 8.77 8.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.04 5.04 5.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database