CHEMBL2163954


SMILES CC1Oc2cccc3c(=O)c(C(=O)NC45CC6CC(CC(C6)C4)C5)cn(c23)C1c1ccccc1
InChIKey RQCZYNKUAQGUIV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Rat Cannabinoid A pKi 6.35 6.35 6.35 ChEMBL
CB1 CNR1 Rat Cannabinoid A pKi 5.58 5.58 5.58 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 6.48 6.48 6.48 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 5.61 5.61 5.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pIC50 5.77 5.77 5.77 ChEMBL