dimaprit


SMILES CN(CCCSC(=N)N)C
InChIKey OLHQOJYVQUNWPL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 161.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 6.1 6.1 6.1 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 4.9 5.7 6.5 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 6.5 6.64 7.05 ChEMBL
H2 HRH2 Human Histamine A pKi 4.6 4.6 4.6 ChEMBL
H3 HRH3 Rat Histamine A pKi 6.36 6.36 6.36 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
H3 HRH3 Human Histamine A pKi 6.08 6.08 6.08 PDSP Ki database
H4 HRH4 Human Histamine A pKi 5.0 5.71 6.42 PDSP Ki database
H2 HRH2 Guinea pig Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
H2 HRH2 Human Histamine A pKi 4.6 5.55 6.5 PDSP Ki database
H3 HRH3 Guinea pig Histamine A pKi 7.32 7.32 7.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 5.8 5.8 5.8 ChEMBL