CHEMBL2057441


SMILES COc1cc2c(c(OC)c1)CN1CCc3cc(OC)c(OC)cc3[C@@H]1C2
InChIKey JVNZVNCHIUVRJV-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.97 7.08 7.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.14 6.14 6.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 6.72 6.83 6.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 6.04 6.04 6.04 ChEMBL