CHEMBL2057451


SMILES COc1cc2c(cc1OC)[C@@H]1Cc3cc(C)cc(C)c3CN1CC2
InChIKey BEZZGCHAIFWOPE-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 323.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.65 6.65 6.65 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 6.17 6.17 6.17 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.94 5.94 5.94 ChEMBL
D2 DRD2 Human Dopamine A pEC50 4.79 4.79 4.79 ChEMBL