CHEMBL2181169


SMILES CCCN1CCC(COc2nc3c(I)cccc3c3ccccc23)CC1
InChIKey UWMNAFXETUEZJZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 460.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 5.24 5.24 5.24 ChEMBL
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.92 8.92 8.92 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.82 6.82 6.82 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.79 6.79 6.79 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.11 6.11 6.11 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database