CHEMBL2181189


SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ccccc23)CC1
InChIKey KMWRABRPTOODHP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 352.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pKi 8.51 8.51 8.51 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.39 7.39 7.39 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.98 5.98 5.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT4 5HT4R Human 5-Hydroxytryptamine A pEC50 7.2 7.2 7.2 ChEMBL