CHEMBL220211


SMILES COc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNC[C@@H]21
InChIKey JCBSTVSERURFTA-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 286.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.76 6.76 6.76 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.96 7.96 7.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.54 6.54 6.54 ChEMBL