CHEMBL218787


SMILES Clc1ccc(N2CCN(Cc3cnn4c(I)cccc34)CC2)cc1
InChIKey DQWYVTVADJXAAR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 452.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.3 8.3 8.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.57 5.57 5.57 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.12 5.12 5.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database