OLCEGEPANT


SMILES NCCCC[C@H](NC(=O)[C@@H](Cc1cc(Br)c(O)c(Br)c1)NC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)C(=O)N1CCN(c2ccncc2)CC1
InChIKey ITIXDWVDFFXNEG-JHOUSYSJSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 5
Rotatable bonds 12
Molecular weight (Da) 867.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
calcitonin-like CALRL Rat Calcitonin B1 pKi 8.47 8.47 8.47 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pKi 10.85 10.94 11.0 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pKd 10.1 10.25 10.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
calcitonin-like CALRL Human Calcitonin B1 pIC50 8.4 9.87 10.7 ChEMBL
calcitonin-like CALRL Human Calcitonin B1 pEC50 10.59 10.59 10.59 ChEMBL