CHEMBL2207632
SMILES | C#Cc1cc(CN2CCN(c3ccccc3OC)CC2)c2cccccc1-2 |
InChIKey | HNCOLMVXXZHGHT-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 356.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Pig | Dopamine | A | pKi | 5.19 | 5.19 | 5.19 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 8.02 | 8.02 | 8.02 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.43 | 6.43 | 6.43 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 7.02 | 7.07 | 7.12 | ChEMBL |
5-HT2A | 5HT2A | Pig | 5-Hydroxytryptamine | A | pKi | 5.68 | 5.68 | 5.68 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |