CHEMBL2207635


SMILES COc1ccccc1N1CCN(Cc2cc(CO)c3cccccc2-3)CC1
InChIKey NUTCIQIPIDPFOT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D1 DRD1 Pig Dopamine A pKi 6.07 6.07 6.07 ChEMBL
H1 HRH1 Human Histamine A pKi 5.85 5.85 5.85 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.15 9.15 9.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.82 7.0 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database