CHEMBL2207638


SMILES COc1ccccc1N1CCN(Cc2cc(CN3CCCCC3)c3cccccc2-3)CC1
InChIKey IOFOPIMDJBEBFZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 429.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
H2 HRH2 Human Histamine A pKi 5.38 5.38 5.38 ChEMBL
H1 HRH1 Human Histamine A pKi 5.26 5.26 5.26 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.72 8.72 8.72 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.8 6.8 6.8 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.29 7.36 7.43 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.39 5.39 5.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database