ACECLIDINE
| SMILES | CC(=O)OC1CN2CCC1CC2 |
| InChIKey | WRJPSSPFHGNBMG-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 1 |
| Molecular weight (Da) | 169.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pKi | 5.65 | 5.93 | 6.21 | PDSP Ki database |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pKi | 5.0 | 5.19 | 5.38 | PDSP Ki database |
| M2 | ACM2 | Rat | Acetylcholine (muscarinic) | A | pKi | 5.0 | 5.18 | 5.36 | PDSP Ki database |
| M3 | ACM3 | Rat | Acetylcholine (muscarinic) | A | pKi | 5.0 | 6.33 | 7.65 | PDSP Ki database |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| M3 | ACM3 | Mouse | Acetylcholine (muscarinic) | A | pEC50 | 5.0 | 5.0 | 5.0 | ChEMBL |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | pIC50 | 5.62 | 6.27 | 6.92 | ChEMBL |
| M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pEC50 | 5.35 | 5.35 | 5.35 | ChEMBL |
| M2 | ACM2 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.24 | 8.24 | 8.24 | Drug Central |
| M1 | ACM1 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.3 | 8.3 | 8.3 | Drug Central |
| M3 | ACM3 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.29 | 8.29 | 8.29 | Drug Central |
| M4 | ACM4 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.32 | 8.32 | 8.32 | Drug Central |
| M5 | ACM5 | Human | Acetylcholine (muscarinic) | A | pEC50 | 8.29 | 8.29 | 8.29 | Drug Central |
| M1 | ACM1 | Rat | Acetylcholine (muscarinic) | A | pIC50 | 8.16 | 8.16 | 8.16 | Drug Central |