CHEMBL2221145


SMILES COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(O)c2O1
InChIKey CQDKZYPQPMHYAR-ZDUSSCGKSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 361.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 8.66 8.66 8.66 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.51 7.51 7.51 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.05 8.05 8.05 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 7.8 7.8 7.8 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 6.78 7.04 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database