CHEMBL2221147


SMILES COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(OC)c2O1
InChIKey UIFMGKZUSHZGFQ-AWEZNQCLSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 9.04 9.04 9.04 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.56 8.56 8.56 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.43 9.43 9.43 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 9.58 9.58 9.58 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.07 9.07 9.07 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 8.55 8.66 8.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database