CHEMBL222782


SMILES O=C(O)c1ccc(CCN2C(=O)CC[C@@H]2/C=C/[C@@H](O)CCC2CCC2)cc1
InChIKey ZWUOWFXIMDPFSC-UNERYHBUSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 371.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pKi 4.1 4.1 4.1 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 9.0 9.0 9.0 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 7.12 7.12 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pEC50 9.7 9.7 9.7 ChEMBL