CHEMBL222933


SMILES c1ccc(-c2ccccc2C2OC2C2=NCCN2)cc1
InChIKey BTPMSDTWDTXFNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 264.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 5.82 5.87 5.91 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 4.7 5.3 5.91 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.19 5.28 5.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pEC50 5.46 5.46 5.46 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 5.57 5.57 5.57 ChEMBL