CHEMBL222973


SMILES Cc1cccc(-c2ccccc2OC(C)C2=NCCN2)c1
InChIKey OITKDPXYSUWTOJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 280.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 7.29 7.29 7.29 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.27 6.27 6.27 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.61 6.61 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 5.8 5.8 5.8 ChEMBL