CHEMBL210404


SMILES COc1ccccc1N1CCN(Cc2cnn(-c3ccccn3)c2)CC1
InChIKey BVXSVALQOFIYSP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 349.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.72 5.72 5.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.36 9.36 9.36 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.14 7.14 7.14 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.4 7.44 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database