CHEMBL210405


SMILES c1ccc(N2CCN(Cc3cnn(-c4ccccc4)c3)CC2)cc1
InChIKey PMMMMZICRVMUKQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 318.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.8 5.8 5.8 ChEMBL
D4 DRD4 Human Dopamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.85 6.96 7.12 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 PDSP Ki database
D1 DRD1 Bovine Dopamine A pKi 5.8 5.8 5.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database