MOPERONE


SMILES Cc1ccc(C2(O)CCN(CCCC(=O)c3ccc(F)cc3)CC2)cc1
InChIKey AGAHNABIDCTLHW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKd 9.02 9.02 9.02 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.14 9.14 9.14 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 PDSP Ki database
D1 DRD1 Bovine Dopamine A pKi 5.92 5.92 5.92 PDSP Ki database
D2 DRD2 Bovine Dopamine A pKi 8.72 8.72 8.72 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.74 8.96 9.15 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 7.57 8.13 8.7 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 9.0 9.5 10.0 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.05 8.05 8.05 Drug Central
D3 DRD3 Human Dopamine A pKi 8.02 8.02 8.02 Drug Central
D4 DRD4 Human Dopamine A pKi 8.09 8.09 8.09 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database