CHEMBL210955


SMILES Clc1ccc(N2CCN(Cc3cnn(-c4ccccc4)c3)CC2)cc1
InChIKey VRWKFSXVIDXVMV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 352.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.12 5.12 5.12 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.54 8.54 8.54 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.72 5.72 5.72 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.6 5.72 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.42 6.42 6.42 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database