CHEMBL211026
SMILES | c1ccc(N2CCN(Cc3cn(-c4ccccc4)nn3)CC2)cc1 |
InChIKey | QLOFPPKCJSHBIO-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 319.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Pig | Dopamine | A | pKi | 4.68 | 4.68 | 4.68 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 8.0 | 8.0 | 8.0 | ChEMBL |
5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 6.32 | 6.32 | 6.32 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.92 | 5.92 | 5.92 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.82 | 5.95 | 6.07 | ChEMBL |
5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 6.32 | 6.32 | 6.32 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |