CHEMBL211118


SMILES COc1ccccc1N1CCN(Cc2cn3cc(C)cc(N4CCOCC4)c3n2)CC1
InChIKey UKYZTZPUJPHXDZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 5.19 5.19 5.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.68 5.68 5.68 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.68 6.84 7.0 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.64 8.64 8.64 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database