CHEMBL2112955


SMILES O=C(CCNC(=O)CNC(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)NC[C@H]1CCCN(CC2CCCCC2)C1
InChIKey VWBQUAMKHIBZSG-JGCGQSQUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 14
Molecular weight (Da) 622.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.43 7.43 7.43 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.85 7.85 7.85 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.51 9.51 9.51 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.52 7.52 7.52 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.92 6.92 6.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database