CHEMBL2112958


SMILES O=C(CCNC(=O)[C@@H]1CCCN1C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)NC[C@H]1CCCN(CC2CCCCC2)C1
InChIKey ZNXQAFLLESPBNZ-BYYXFNHRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 13
Molecular weight (Da) 662.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.24 7.24 7.24 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.96 7.96 7.96 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.33 9.33 9.33 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.82 6.82 6.82 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database