CHEMBL22961


SMILES NC(=O)c1ccc2[nH]cc(C3=CCC(NCCCCCCCCNC4CC=C(c5c[nH]c6ccc(C(N)=O)cc56)CC4)CC3)c2c1
InChIKey QXXXZTFUFKESQI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 6
Rotatable bonds 15
Molecular weight (Da) 620.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 9.96 9.96 9.96 ChEMBL
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pIC50 6.41 6.41 6.41 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 8.67 8.67 8.67 ChEMBL