CHEMBL2113386


SMILES O=S(=O)(Cc1ccccc1I)Nc1ccc2[nH]cc(C[C@H]3CCCN3)c2c1
InChIKey DXNOFPQQCQAJFH-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 495.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 7.75 7.75 7.75 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 8.03 8.03 8.03 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.19 7.19 7.19 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.48 6.48 6.48 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 9.4 9.4 9.4 ChEMBL