GR-55562


SMILES CN(CCCc1cc(ccc1O)C(=O)Nc1ccc(cc1)c1ccncc1)C
InChIKey ZAGAUUVCYGSPBP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 Guide to Pharmacology
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.16 6.16 6.16 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.85 7.88 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKB 7.4 7.4 7.4 Guide to Pharmacology