GSK1331268


SMILES Clc1cnc(nc1)N1CCN(CC1)Cc1nc2c(n1C)cccc2
InChIKey IXXZGBOSQDVMTC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 342.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.6 5.6 5.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 6.9 6.9 6.9 Guide to Pharmacology
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.9 6.4 6.9 ChEMBL